Hydroxypropyl Methylcellulose (HPMC) ke motsoako o sebetsang ka bongata o sebelisoang haholo liindastering tse fapaneng ka lebaka la thepa ea ona e ikhethang.Sengoliloeng sena se kenella ka har'a lintho tse rarahaneng tsa HPMC, ho hlahloba sebopeho sa eona sa lik'hemik'hale, thepa, mesebetsi le lits'ebetso tse fapaneng.Ho tloha ho litlhare ho isa ho tsa kaho, lihlahisoa tsa lijo ho isa linthong tsa tlhokomelo ea motho, HPMC e bapala karolo ea bohlokoa, e bonts'ang bohlokoa ba eona ho nts'etsopele ea sejoale-joale ea tlhahiso le lihlahisoa.
Hydroxypropyl Methylcellulose (HPMC) ke motsoako oa selulose o fetotsoeng ka lik'hemik'hale o fumanang tšebeliso e pharaletseng liindastering ho tloha ho meriana ho ea ho haha, lijo le tlhokomelo ea botho.Mehaho ea eona e ikhethang e etsa hore e be ea bohlokoa haholo lits'ebetsong tse fapaneng, e kenya letsoho ho tsitsang, viscosity le ts'ebetsong ea lihlahisoa tse ngata.
1.Sebopeho sa Lik'hemik'hale le Thepa
HPMC e entsoe ka karabelo ea alkali cellulose e nang le methyl chloride le propylene oxide, e bakang ho nkeloa sebaka ha lihlopha tsa hydroxyl ka ketane ea cellulose ka hydroxypropyl le lihlopha tsa methoxy.Phetoho ena e fana ka thepa e ikhethang ho HPMC, ho kenyelletsa le ho qhibiliha ha metsi, ho futhumatsa ha mocheso, bokhoni ba ho etsa lifilimi, le taolo e ntle ea rheological.
Tekanyo ea ho fetola (DS) le boima ba molek'hule li susumetsa haholo thepa ea HPMC.DS e phahameng e ntlafatsa ho qhibiliha ha metsi le ho fokotsa mocheso oa gelation, ha boima ba limolek'hule bo ama viscosity le litšobotsi tsa ho etsa filimi.Thepa ena e ka sebelisoang e etsa hore HPMC e ikamahanye le mefuta e mengata ea lits'ebetso.
2.Mesebetsi ea HPMC
Taolo ea Thickening le Rheology: HPMC e sebetsa e le ntho e teteaneng ka har'a litharollo tse nang le metsi, e fana ka viscosity le ho matlafatsa botsitso ba metsoako.Boitšoaro ba eona ba pseudoplastic bo lumella taolo e nepahetseng ea rheological, e nolofalletsa tlhahiso ea lihlahisoa tse nang le thepa ea phallo e lakatsehang.
Tlhahiso ea Lifilimi: Ka lebaka la bokhoni ba eona ba ho etsa lifilimi tse pepeneneng le tse tenyetsehang ha li omisoa, HPMC e sebelisoa haholo ka liphahlo, matlapa a meriana le lihlahisoa tsa tlhokomelo ea motho.Lifilimi tsena li fana ka thepa ea thibelo, ho boloka mongobo, le ho lokolloa ho laoloang ha metsoako e sebetsang.
Ho Boloka Metsi: Linthong tsa kaho tse kang seretse, lipolasetere le likhomaretsi, HPMC e ntlafatsa ts'ebetso le ho thibela tahlehelo ea metsi ka potlako nakong ea ho folisa.Sena se matlafatsa ho khomarela, se fokotsa ho phunyeha, 'me se tiisa hore ho na le metsi a tšoanang a metsoako ea cementitious.
Binder le Disintegrant: Metsoakong ea meriana, HPMC e sebetsa e le tlamahano, e tšoarang metsoako e sebetsang hammoho matlapeng, li-capsules le granules.Ho phaella moo, bokhoni ba eona ba ho ruruha le ho arohana ka lithuso tsa mecha ea litaba tse nang le metsi ka mokhoa o laoloang oa ho lokolloa ha lithethefatsi.
Stabilizer le Emulsifier: HPMC e tsitsisa ho emisoa, li-emulsion, le foam lijong, litlolo, le lits'ebetsong tsa indasteri.E thibela karohano ea mekhahlelo, e boloka sebopeho, 'me e ntlafatsa bophelo ba sethala ka ho thibela kholo ea likokoana-hloko le oxidation.
3.Likopo tsa HPMC
Meriana: HPMC ke motsoako oa mantlha mefuteng ea litekanyetso tse tiileng tsa molomo joalo ka matlapa, li-capsules le li-pellets.Karolo ea eona e le setlamo, se arolang, le moemeli oa tokollo e laoloang e netefatsa katleho, polokeho, le ho latela mamello ea lihlahisoa tsa meriana.
Kaho: indastering ea kaho, HPMC e eketsoa lisebelisoa tse thehiloeng ho samente ho ntlafatsa ts'ebetso, ho boloka metsi le thepa ea sekhomaretsi.E ntlafatsa ts'ebetso ea lirafshoa, li-plaster, li-grouts le li-renders, tse lebisang ho meaho e tšoarellang le e khahlisang ka bokhabane.
Lijo le Lino: HPMC e fumana ts'ebeliso ea lihlahisoa tsa lijo e le setenya, se tsitsitseng, le emulsifier.E sebelisoa hangata ho li-sauces, li-dressings, mefuta e meng ea lebese, le lintho tsa ho baka ho ntlafatsa sebopeho, molomo le botsitso ba sethala.
Tlhokomelo ea Botho: Ka litlolo le lihlahisoa tsa tlhokomelo ea motho, HPMC e sebetsa joalo ka filimi ea pele, e teteaneng le e emisang.E fumaneha ka har'a litlolo, litlolo, li-shampoo le sesepa sa meno, e fana ka lintho tse lakatsehang tsa kutlo le ho ntlafatsa ts'ebetso ea sehlahisoa.
Lipente le Likhabiso: HPMC e sebelisoa ka lipente tse thehiloeng metsing, liphahlo le likhomaretsi ho lokisa viscosity, ho ntlafatsa ho hanyetsa le ho ntlafatsa sebopeho sa filimi.E khothalletsa ts'ebeliso e ts'oanang, ho khomarela li-substrates, le ho tšoarella ha likhahla tse holimo.
4. Maikutlo a Bokamoso le Mathata
Leha e na le ts'ebeliso e atileng le ho feto-fetoha ha maemo, liphephetso tse joalo ka phapang ea batch-to-batch, menahano ea taolo, le mathata a tikoloho li ntse li tsoela pele tlhahisong le ts'ebelisong ea HPMC.Boiteko ba lipatlisiso ba nako e tlang bo ikemiselitse ho rarolla mathata ana ha ho ntse ho hlahlojoa lits'ebetso tse ncha le litsela tse tsitsitseng tsa ho kopanya tse tsoang ho HPMC.
Hydroxypropyl Methylcellulose (HPMC) ke motsoako o sebetsang ka bongata o nang le lisebelisoa tse fapaneng ho pholletsa le meriana, kaho, lijo, tlhokomelo ea botho le indasteri.Motsoako oa eona o ikhethang oa thepa, ho kenyeletsoa ho tenya, ho etsa lifilimi, ho boloka metsi, le bokhoni ba ho tsitsisa, ho etsa hore e be ea bohlokoa haholo tlhahisong ea sejoale-joale le nts'etsopele ea lihlahisoa.Ka ho utloisisa sebopeho sa lik'hemik'hale, thepa le mesebetsi ea HPMC, liindasteri li ka sebelisa bokhoni ba tsona ba ho theha liforomo tse ncha le tse sebetsang hantle tse fihlelang litlhoko tse ntseng li tsoela pele tsa bareki le limmaraka.
Nako ea poso: Feb-29-2024