Lefapheng la mahlale a thepa le kaho, li-additives li phetha karolo ea bohlokoa ho ntlafatseng thepa e fapaneng.Hydroxypropyl methylcellulose (HPMC) ke e 'ngoe ea tlatsetso e joalo e fumaneng tlhokomelo e kholo bakeng sa bokhoni ba eona ba ho ntlafatsa thepa ea sekhomaretsi lits'ebetsong tse fapaneng.
Li-additives ke karolo ea bohlokoa lefapheng la mahlale a thepa 'me hangata li sebelisoa ho ntlafatsa thepa ea thepa e fapaneng.Har'a li-additives tsena, hydroxypropyl methylcellulose (HPMC) e fetohile sebapali sa bohlokoa, haholo-holo ho ntlafatsa thepa ea ho khomarela.Thepa ea sekhomaretsi e bohlokoa haholo liindastering tse ngata, ho kenyelletsa kaho, meriana le lijo, moo matla le ho tšoarella ha bond li amang haholo ts'ebetso le bophelo bo bolelele ba sehlahisoa.
1. Utloisisa Hydroxypropyl Methylcellulose (HPMC)
Hydroxypropyl methylcellulose (HPMC) ke motsoako oa selulose 'me e sebelisoa haholo liindastering tse fapaneng ka lebaka la thepa ea eona e mengata.E entsoe ka phetoho ea lik'hemik'hale ea selulose, moo lihlopha tsa hydroxypropyl le methyl li kenngoa mokokotlong oa cellulose.Phetoho ena e fana ka thepa e ikhethang ea motsoako, ho kenyelletsa le ho qhibiliha ha metsi a mangata, bokhoni ba ho etsa lifilimi, 'me haholo-holo, bokhoni ba ho ntlafatsa thepa ea sekhomaretsi.
2.Mochine oo HPMC e ntlafatsang thepa ea ho khomarela
Bokhoni ba HPMC ba ho ntlafatsa thepa ea sekhomaretsi bo bakoa ke sebopeho sa eona sa limolek'hule le ho sebelisana le lintho tse ling.Ha e qhibiliha ka metsing, limolek'hule tsa HPMC li hydrate, li etsa tharollo ea viscous.Tharollo e sebetsa e le setlamo, se khothalletsang ho thehoa ha maqhama a matla pakeng tsa likaroloana kapa libaka.Ho phaella moo, limolek'hule tsa HPMC li na le lihlopha tse sebetsang tse ka sebelisanang le sebaka sa substrate, ho khothalletsa ho khomarela le ho kopana.Litšebelisano tsena li thusa ho ntlafatsa ho kolobisa, ho ata le ho khomarela sefahleho, e leng lintlha tsa bohlokoa ho finyella maqhama a matla le a nako e telele.
3. Tšebeliso ea HPMC liindastering tse fapaneng
Ho feto-fetoha ha maemo ha HPMC ho etsa hore e be ea bohlokoa haholo ho liindasteri tse fapaneng.Lefapheng la kaho, HPMC e sebelisoa hangata joalo ka tlatsetso ea thepa e thehiloeng ho samente joalo ka seretse le konkreite.Ka ho ntlafatsa maqhama pakeng tsa likaroloana tsa samente le kakaretso, HPMC e eketsa matla, ho sebetsa le ho tšoarella ha lisebelisoa tsena.Ka mokhoa o ts'oanang, indastering ea meriana, HPMC e sebelisoa mefuteng ea letlapa ho ntlafatsa motsoako oa phofo le ho netefatsa hore ho lokolloa ha lithethefatsi tse tšoanang.Ho feta moo, indastering ea lijo, HPMC e sebelisoa e le sethapo le setenya, se thusa ho ntlafatsa sebopeho le ponahalo ea lijo ha li ntse li eketsa bophelo ba tsona.
4. Mohlala: Tšebeliso e sebetsang ea HPMC
Ho tsoela pele ho bonts'a katleho ea HPMC ho ntlafatseng thepa ea tlamahano, lithuto tse 'maloa li ka hlahlojoa.Lefapheng la kaho, phuputso e mabapi le tšebeliso ea HPMC ka har'a seretse sa ho itšebetsa e bonts'itse keketseho e kholo ea matla a bond le khanyetso ea crack.Ka mokhoa o ts'oanang, litlhahlobong tsa meriana, liphuputso li bonts'itse hore matlapa a nang le HPMC a bonts'a thepa e phahameng ea mochini le profil ea ho qhibiliha ha e bapisoa le matlapa a se nang HPMC.Lithuto tsena tsa linyeoe li totobatsa bohlokoa ba HPMC lits'ebetsong tsa lefats'e la nnete, e totobatsang katleho ea eona ho ntlafatseng thepa ea maqhama ho liindasteri tse fapaneng.
5. Litebello le mathata a kamoso
Ho ea pele, ts'ebeliso ea li-additives tse kang HPMC ho ntlafatsa thepa ea tlamo e tšepisa kholo e tsoelang pele le boqapi.Tsoelo-pele ea mahlale a thepa le boenjineri ba lik'hemik'hale e ka lebisa ho nts'etsopele ea li-additives tse ncha ka katleho e kholo le ho feto-fetoha ha maemo.Leha ho le joalo, liqholotso tse kang ho boloka litšenyehelo, ho tšoarella ha tikoloho le ho lumellana le melao ea tsamaiso li tlameha ho rarolloa ho etsa bonnete ba ho amoheloa hohle ha lisebelisoa tsena.Ho feta moo, lipatlisiso tse ling lia hlokahala ho utloisisa ka botlalo mekhoa ea ts'ebetso le ho ntlafatsa tlhahiso le ts'ebeliso ea lihlahisoa tse thehiloeng ho HPMC.
Li-additives tse kang hydroxypropyl methylcellulose (HPMC) li bapala karolo ea bohlokoa ho ntlafatsa ho khomarela.Ding Property e akaretsa maemo ohle a bophelo.Ka sebopeho sa eona se ikhethang sa limolek'hule le litšebelisano, HPMC e ntlafatsa ho khomarela, ho kopanya le ho kopanya sefahleho, ka hona ho matlafatsa maqhama pakeng tsa likaroloana kapa libaka.Ho ikamahanya le maemo le ho sebetsa ha eona ho etsa hore e be ea bohlokoa haholo lits'ebetsong tse kang kaho, meriana le lijo.Ha lipatlisiso le nts'etsopele li ntse li tsoela pele, bokamoso bo fana ka menyetla e mengata ea ho ntlafatsa le ho sebelisa HPMC le litlatsetso tse ts'oanang ho ntlafatsa ts'ebetso ea tlamahano le ho khanna boqapi le botsitso ho boenjineri ba thepa.
Nako ea poso: Feb-28-2024