Tšebeliso ea HPMC Lefapheng la Meriana

Hydroxypropyl methylcellulose (HPMC), eo hape e tsejoang e le hypromellose, e sebelisoa haholo indastering ea meriana ka lebaka la thepa ea eona e fapaneng.Mona ke tse ling tsa lits'ebetso tse tloaelehileng tsa HPMC litlameng tsa meriana:

1. Letlapa Binder: HPMC e sebelisoa hangata joalo ka setlamo mefuteng ea matlapa ho fana ka momahano le ho ntlafatsa ho thatafala ha letlapa.E thusa ho tšoara metsoako ea phofshoana hammoho nakong ea ho hatella, ho fella ka matlapa a nang le ho tšoana le matla a mochine.
2. Film Coating Agent: HPMC e sebelisoa e le moemeli oa ho roala filimi ho fana ka tšireletso le / kapa seaparo se setle holim'a matlapa le li-capsules.Ho roala filimi ho ntlafatsa ponahalo, tatso ea masking, le botsitso ba foromo ea litekanyetso tsa meriana.Ho feta moo, e ka laola kinetics ea tokollo ea lithethefatsi, ea sireletsa sethethefatsi ho tloha mongobo, 'me ea nolofatsa ho metsa.
3. Matrix Former: HPMC e sebelisoa e le matrix ea pele ho liforomo tsa matlapa tse laoloang le tse lokollotsoeng ka nako e telele.E theha gel layer holim'a hydration, e laolang ho hasana ha moriana ho tloha foromong ea litekanyetso, e lebisang ho lokolloa ha lithethefatsi nako e telele le phello e tsitsitseng ea phekolo.
4. Disintegrant: Litlhahiso tse ling, HPMC e ka sebetsa e le e senyang, e khothalletsang karohano e potlakileng le ho hasana ha matlapa kapa li-capsules ka har'a pampiri ea mala.Sena se thusa ho qhala le ho monya ha lithethefatsi, ho netefatsa bioavailability e nepahetseng.
5. Viscosity Modifier: HPMC e sebelisoa joalo ka sebopeho sa viscosity mekhoeng ea mokelikeli le e batlang e tiile joalo ka li-suspensions, li-emulsion, li-gel, le litlolo.E fana ka taolo ea rheological, e ntlafatsa botsitso ba ho fanyeha, 'me e matlafatsa ho ata le ho khomarela ha metsoako ea lihlooho.
6. Stabilizer le Emulsifier: HPMC e sebelisoa e le stabilizer le emulsifier ka metsoako ea metsi ho thibela karohano ea mekhahlelo, ho ntlafatsa botsitso ba ho emisa, le ho ntlafatsa homogeneity ea sehlahisoa.Hangata e sebelisoa ha ho emisoa ka molomo, li-syrups le li-emulsions.
7. Thickening Agent: HPMC e sebelisoa e le ntho e matlafatsang mefuteng e fapaneng ea meriana ho eketsa viscosity le ho fana ka thepa e lakatsehang ea rheological.E ntlafatsa sebopeho le ho tsitsisa ha litokisetso tsa lihlooho tse kang litlolo, li-lotion le li-gel, ho matlafatsa ho ata ha tsona le ho ikutloa ha letlalo.
8. Opacifier: HPMC e ka sebelisoa e le sesebelisoa sa opacifying mefuteng e itseng ho fana ka taolo ea opacity kapa opacity.Thepa ena e na le thuso ka ho khetheha ho ophthalmic formulations, moo opacity e ka ntlafatsang ponahalo ea sehlahisoa nakong ea tsamaiso.
9. Koloi bakeng sa Mekhoa ea Phano ea Lithethefatsi: HPMC e sebelisoa e le koloi kapa sejari mekhoeng ea ho fana ka lithethefatsi tse kang microspheres, nanoparticles, le hydrogels.E ka kenyelletsa lithethefatsi, ea laola kinetics ea ho lokolloa ha lithethefatsi, le ho matlafatsa botsitso ba lithethefatsi, ho fana ka phano ea lithethefatsi e lebisitsoeng le e laoloang.

HPMC ke setsebi sa meriana se nang le mekhoa e mengata e fapaneng ea lisebelisoa, ho kenyelletsa le ho tlama letlapa, ho roala filimi, ho thehoa ha matrix a laoloang, ho arohana, phetoho ea viscosity, stabilization, emulsification, thickening, opacification, le tlhahiso ea tsamaiso ea tsamaiso ea lithethefatsi.Tšebeliso ea eona e kenya letsoho ntlafatsong ea lihlahisoa tsa meriana tse bolokehileng, tse sebetsang hantle le tse bonolo ho mokuli.