E le ho bapisa CMC (carboxymethylcellulose) le HPMC (hydroxypropylmethylcellulose), re lokela ho utloisisa thepa ea bona, likopo, melemo, mathata, le linyeoe tse ka sebelisoang. Li-derivatives ka bobeli tsa cellulose li sebelisoa haholo liindastering tse fapaneng, ho kenyeletsoa meriana, lijo, litlolo le kaho. E 'ngoe le e' ngoe e na le thepa e ikhethang e etsang hore e tšoanelehe bakeng sa merero e fapaneng. Ha re etseng papiso e tebileng e felletseng ho bona hore na ke ofe ea molemo maemong a fapaneng.
1. Tlhaloso le sebopeho:
CMC (carboxymethylcellulose): CMC ke motsoako oa selulose o qhibilihang ka metsing o hlahisoang ke karabelo ea selulose le chloroacetic acid. E na le lihlopha tsa carboxymethyl (-CH2-COOH) tse kopantsoeng le lihlopha tse ling tsa hydroxyl tsa glucopyranose monomers tse etsang mokokotlo oa cellulose.
HPMC (hydroxypropyl methylcellulose): HPMC hape ke motsoako oa selulose o qhibilihang ka metsing o hlahisoang ka ho phekola selulose ka propylene oxide le methyl chloride. E na le lihlopha tsa hydroxypropyl le methoxy tse khomaretsoeng mokokotlong oa cellulose.
2. Sollubility:
CMC: E qhibiliha haholo ka metsing, e etsa tharollo e hlakileng, e nang le viscous. E bonts'a boits'oaro ba phallo ea pseudoplastic, ho bolelang hore viscosity ea eona e ea fokotseha tlasa khatello ea ho kuta.
HPMC: E boetse e qhibiliha ka metsing, e etsa tharollo ea viscous hanyenyane ho feta CMC. E boetse e bontša boitšoaro ba pseudoplastic.
3. Lintho tsa Rheological:
CMC: E bonts'a boitšoaro ba ho kuta, ho bolelang hore viscosity ea eona e fokotseha ka sekhahla se ntseng se eketseha sa ho kuta. Thepa ena e etsa hore e tšoanelehe bakeng sa lits'ebetso moo ho hlokahalang hore ho be thata empa tharollo e hloka ho phalla habonolo tlas'a ho kuta, joalo ka lipente, li-detergents le meriana.
HPMC: e bonts'a boits'oaro bo ts'oanang ba rheological ho CMC, empa viscosity ea eona hangata e phahame maemong a tlase. E na le thepa e ntle ea ho etsa lifilimi, e etsa hore e tšoanelehe bakeng sa likopo tse kang ho roala, li-adhesives le mekhoa ea meriana e laoloang.
4. Botsitso:
CMC: Ka kakaretso e tsitsitse ho feta mefuta e mengata ea pH le mocheso. E ka mamella maemo a itekanetseng a electrolyte.
HPMC: E tsitsitse ho feta CMC tlasa maemo a asiti, empa e ka ba le hydrolysis tlasa maemo a alkaline. E boetse e na le kutloelo-bohloko ho li-cations tsa divalent, tse ka bakang gelation kapa pula.
5. Kopo:
CMC: ho pharaletseng sebelisoa e le thickener, stabilizer le ho boloka metsi a moemeli lijo (tse kang ice cream, soso), meriana (joaloka matlapa, ho fanyeha) le litlolo (tse kang tranelate, lotion) indasteri.
HPMC: Hangata e sebelisoa linthong tsa kaho (mohlala, likhomaretsi tsa lithaele tsa samente, samente, seretse), meriana (mohlala, matlapa a lokolotsoeng ka taolo, litokisetso tsa mahlo), le litlolo (mohlala, marotholi a mahlo, lihlahisoa tsa tlhokomelo ea letlalo).
6. Chefo le polokeho:
CMC: Ka kakaretso e amoheloa e le e bolokehileng (GRAS) ke mekhatlo ea taolo ha e sebelisoa ka har'a meeli e behiloeng lits'ebetsong tsa lijo le tsa meriana. Ha e na chefo ebile ha e chefo.
HPMC: E boetse e nkuoa e bolokehile hore e ka sebelisoa ka har'a meeli e khothaletsoang. E na le biocompatible 'me e sebelisoa haholo lefapheng la meriana e le moemeli ea laoloang oa tokollo le binder ea matlapa.
7. Litšenyehelo le ho ba Teng:
CMC: Ka tloaelo e bitsa chelete e ngata ho feta HPMC. E fumaneha habonolo ho tsoa ho barekisi ba fapaneng lefatšeng ka bophara.
HPMC: E theko e phahameng hanyane ka lebaka la ts'ebetso ea eona ea tlhahiso le phepelo e fokolang ka linako tse ling ho tsoa ho barekisi ba itseng.
8. Tšusumetso ea tikoloho:
CMC: Biodegradable, e nkiloeng mehloling e ka nchafatsoang (selulose). E nkoa e le botsoalle ho tikoloho.
HPMC: Hape ke biodegradable le e nkiloeng ho selulose, kahoo hape haholo botsoalle tikoloho.
Ka bobeli CMC le HPMC li na le thepa e ikhethang e li etsang litlatsetso tsa bohlokoa liindastering tse ngata. Khetho pakeng tsa bona e itšetlehile ka litlhoko tse khethehileng tsa kopo tse kang solubility, viscosity, botsitso le ho nahanela litšenyehelo. Ka kakaretso, CMC e kanna ea ratoa ka lebaka la theko ea eona e tlase, botsitso bo pharalletseng ba pH, le ho tšoaneleha bakeng sa lisebelisoa tsa lijo le litlolo. HPMC, ka lehlakoreng le leng, e kanna ea ratoa bakeng sa viscosity ea eona e holimo, thepa e ntle ea ho etsa lifilimi, le ts'ebeliso ea litlhare le lisebelisoa tsa kaho. Qetellong, khetho e lokela ho ipapisa le ho shebisisa lintlha tsena ka botlalo le ho lumellana le ts'ebeliso e reriloeng.
Nako ea poso: Feb-21-2024