Hydroxypropyl Methylcellulose (HPMC) ke polymer e feto-fetohang e fumanang lits'ebetso tse ngata liindastering tse fapaneng, ho kenyeletsoa meriana, lijo, kaho le litlolo.
1. Selelekela ho HPMC:
Hydroxypropyl Methylcellulose (HPMC) ke semi-synthetic, inert, viscoelastic polymer e nkiloeng ho selulose. E entsoe ka phetoho ea lik'hemik'hale ea selulose, e kenyelletsang etherification ea alkali cellulose ka propylene oxide le methyl chloride. Sehlahisoa se hlahisoang ke phofo e tšoeu ho isa ho bosoeu, e sa nkhang hamonate, 'me e sa latsoehe, e qhibilihang metsing empa e sa qhibilihe ka har'a metsoako ea tlhaho.
2. Sebopeho le Thepa:
Sebopeho sa HPMC se na le mokokotlo oa selulose, polima ea tlhaho e entsoeng ka likaroloana tsa tsoekere tse hokahantsoeng ka libonto tsa β(1→4) tsa glycosidic. Ho HPMC, lihlopha tse ling tsa hydroxyl ho li-glucose li kenngoa sebakeng sa 2-hydroxypropyl le lihlopha tsa methyl. Phetolelo ena e fetola thepa ea polymer ha e bapisoa le selulose ea tlhaho, e fana ka ho qhibiliha ho ntlafalitsoeng, viscosity le bokhoni ba ho etsa lifilimi.
Thepa ea HPMC e fapana ho latela lintlha tse kang degree of substitution (DS), boima ba molek'hule, le kabo ea boholo ba likaroloana. Ka kakaretso, HPMC e bonts'a:
Lintho tse ntle tsa ho etsa lifilimi
Boitšoaro ba gelation ea mocheso
Bokhoni bo phahameng ba ho boloka metsi
Ho ba le botsitso holim'a mefuta e mengata ea pH
Ho lumellana le li-polymers tse ling le li-additives
Tlhaho e seng ea ionic, e etsang hore e lumellane le lisebelisoa tse fapaneng
3. Tšimoloho ea HPMC:
The synthesis ea HPMC e kenyelletsa mehato e mengata:
Alkali cellulose lokisetsa: Cellulose e phekoloa ka tharollo ea alkaline ho etsa alkali cellulose.
Etherification: Alkali cellulose e sebetsana le propylene oxide le methyl chloride ho hlahisa hydroxypropyl le lihlopha tsa methyl mokokotlong oa cellulose.
Ho hlatsoa le ho hloekisoa: Sehlahisoa se hlahisoang sea hlatsuoa, ha se na letho, 'me se hloekisoa ho tlosa litšila.
Ho omisa: HPMC e hloekisitsoeng e omisitsoe ho fumana sehlahisoa sa ho qetela ka mokhoa oa phofo.
4. Likopo tsa HPMC:
HPMC e fumana lits'ebetso tse atileng ho liindasteri tse fapaneng:
Meriana ea Meriana: HPMC e sebelisoa ka mokhoa o pharaletseng e le mothusi oa meriana ka har'a litlolo tsa letlapa, litlhophiso tse laoloang tse lokolloang, litokisetso tsa mahlo, le ho emisoa. E sebetsa joalo ka setlamo, setenya, sa pele sa filimi, le se lokollang nako e telele ka mefuta e fapaneng ea litekanyetso.
Indasteri ea Lijo: Indastering ea lijo, HPMC e sebelisoa e le setei, se tsitsitseng, se emulsifier le se bolokang mongobo lihlahisoa tse kang thepa e halikiloeng, lihlahisoa tsa lebese, li-sauces le li-dessert. E ntlafatsa sebopeho, bophelo ba sethala, le molomo oa lihlahisoa tsa lijo.
Kaho: HPMC ke motsoako oa mantlha oa thepa ea kaho joalo ka lirekere tse thehiloeng ho samente, likhomaretsi tsa lithaele, le lihlahisoa tse thehiloeng ho gypsum. E sebetsa e le sesebelisoa sa ho boloka metsi, e ntlafatsa ts'ebetso, e fokotsa ho fokotseha, 'me e matlafatsa ho khomarela libopeho tsa kaho.
Litlolo: HPMC e sebelisoa ho litlolo le lihlahisoa tsa tlhokomelo ea motho e le ntho e teteaneng, e tsitsitseng, le e etsang lifilimi lihlahisoa tse kang litlolo, litlolo, li-shampoo le li-gel. E fana ka viscosity, e ntlafatsa sebopeho, 'me e fana ka maikutlo a boreleli, a se nang mafura.
Lisebelisoa tse Ling: HPMC e boetse e sebelisoa ho hatisa masela, lirafshoa, lipente, litlolo, le joalo ka setlolo lits'ebetsong tse fapaneng tsa indasteri.
5. Maikutlo a Bokamoso le Liphephetso:
Tlhokahalo ea HPMC e lebelletsoe ho tsoela pele ho hola ka lebaka la thepa ea eona e fapaneng le lits'ebetso tse fapaneng. Leha ho le joalo, liqholotso tse kang ho feto-fetoha ha litheko tsa thepa e tala, lithibelo tsa taolo, le tlholisano ho tsoa ho lipolymer tse ling li ka ama matla a 'maraka. Boiteko ba lipatlisiso bo tsepamisitse maikutlo ho ntlafatseng ts'ebetso ea HPMC, ho lekola mekhoa e tsitsitseng ea ho kopanya, le ho holisa ts'ebeliso ea eona mafapheng a ntseng a hlaha joalo ka biomedicine le nanotechnology.
Hydroxypropyl Methylcellulose (HPMC) ke polymer ea bohlokoa e nang le mefuta e mengata ea lisebelisoa ho pholletsa le liindasteri tse ngata. Sebopeho sa eona se ikhethileng, thepa le motsoako o e etsa motsoako oa bohlokoa ho tsa meriana, lihlahisoa tsa lijo, thepa ea kaho, litlolo le lits'ebetso tse fapaneng tsa indasteri. Ha boiteko ba lipatlisiso le nts'etsopele bo ntse bo tsoela pele, HPMC e ikemiselitse ho lula e le sebapali sa bohlokoa indastering ea polymer, e fanang ka litharollo tse ncha ho fihlela litlhoko tsa 'maraka tse ntseng li tsoela pele.
Nako ea poso: Mar-05-2024