Hydroxypropyl methylcellulose (HPMC) ke polymer e feto-fetohang e nang le thepa ea hydrophobic le hydrophilic, e e etsa e ikhethang lits'ebetsong tse fapaneng ho pholletsa le liindasteri tse fapaneng. Bakeng sa ho utloisisa hydrophobicity le hydrophilicity ea HPMC, re hloka ho ithuta sebopeho sa eona, thepa le lits'ebetso ka botebo.
Sebopeho sa hydroxypropyl methylcellulose:
HPMC e tsoa ho cellulose, polima ea tlhaho e fumanehang maboteng a lisele tsa semela. Phetoho ea selulose e kenyelletsa ho kenngoa ha lihlopha tsa hydroxypropyl le methyl mokokotlong oa cellulose. Phetoho ena e fetola thepa ea polymer, e fana ka thepa e khethehileng e molemo bakeng sa mefuta e mengata ea likopo.
Hydrophilicity ea HPMC:
Hydroxy:
HPMC e na le dihlopha tsa hydroxypropyl mme ke hydrophilic. Lihlopha tsena tsa hydroxyl li na le kamano e phahameng ea limolek'hule tsa metsi ka lebaka la ho kopana ha haedrojene.
Sehlopha sa Hydroxypropyl se ka theha likamano tsa haedrojene ka limolek'hule tsa metsi, ho etsa hore HPMC e qhibilihe ka metsing ho isa tekanyong e itseng.
methyl:
Le hoja sehlopha sa methyl se kenya letsoho ho hydrophobicity ka kakaretso ea molek'hule, ha e hanyetsane le hydrophilicity ea sehlopha sa hydroxypropyl.
Sehlopha sa methyl ha se na polar, empa boteng ba sehlopha sa hydroxypropyl bo khetholla sebopeho sa hydrophilic.
Hydrophobicity ea HPMC:
methyl:
Lihlopha tsa methyl ho HPMC li fumana ho isa bohōleng bo itseng hydrophobicity ea eona.
Leha e se joalo ka hydrophobic joalo ka lipolima tse ling tse entsoeng ka botlalo, boteng ba lihlopha tsa methyl bo fokotsa hydrophilicity ka kakaretso ea HPMC.
Litšobotsi tsa ho etsa lifilimi:
HPMC e tsebahala ka thepa ea eona ea ho etsa lifilimi, 'me hangata e sebelisoa hampe litlhare le litlolo. Hydrophobicity e kenya letsoho ho thehoeng ha filimi e sireletsang.
Litšebelisano le lintho tse seng polar:
Lits'ebetsong tse ling, HPMC e ka sebelisana le lintho tse seng polar ka lebaka la karolo ea eona ea hydrophobicity. Thepa ena e bohlokoa bakeng sa lits'ebetso tsa phano ea lithethefatsi indastering ea meriana.
Lisebelisoa tsa HPMC:
lithethefatsi:
HPMC e sebelisoa haholo mekhoeng ea meriana e le setlamo, sa pele sa filimi, le se feto-fetohang sa viscosity. Bokhoni ba eona ba ho etsa lifilimi bo thusa ho lokolloa ha lithethefatsi ka tsela e laoloang.
E sebelisoa mefuteng ea litekanyetso tse tiileng tsa molomo joalo ka matlapa le li-capsules.
Indasteri ea kaho:
Lefapheng la kaho, HPMC e sebelisoa lihlahisoa tse thehiloeng ho samente ho ntlafatsa ts'ebetso, ho boloka metsi le ho khomarela.
Hydrophilicity e thusa ho boloka metsi, ha hydrophobicity e thusa ho ntlafatsa ho khomarela.
indasteri ea lijo:
HPMC e sebelisoa e le setei se teteaneng le se etsang gelling indastering ea lijo. Sebopeho sa eona sa hydrophilic se thusa ho theha li-gel tse tsitsitseng le ho laola viscosity ea lihlahisoa tsa lijo.
cosmetic:
Ka litlolo tsa litlolo, HPMC e sebelisoa lihlahisoa tse kang litlolo le litlolo ka lebaka la thepa ea eona ea ho etsa lifilimi le ho tenya.
Hydrophilicity e netefatsa hore letlalo le na le metsi hantle.
ha re phethela:
HPMC ke polima hore ke ka bobeli hydrophilic le hydrophobic. Tekanyo lipakeng tsa hydroxypropyl le lihlopha tsa methyl sebopeho sa eona e e fa matla a ikhethang, a e lumellang ho ba le mefuta e mengata ea lits'ebetso. Ho utloisisa thepa ena ho bohlokoa bakeng sa ho loants'a HPMC ts'ebelisong e ikhethileng indastering e fapaneng, moo bokhoni ba HPMC ba ho sebelisana le metsi le lintho tse seng polar bo sebelisetsoa merero e fapaneng.
Nako ea poso: Dec-15-2023