Hydroxypropyl methylcellulose (HPMC) ke polymer e feto-fetohang e nang le thepa ea hydrophobic le hydrophilic, e e etsa e ikhethang lits'ebetsong tse fapaneng ho pholletsa le liindasteri tse fapaneng. E le ho utloisisa hydrophobicity le hydrophilicity ea HPMC, re hloka ho ithuta sebopeho sa eona, thepa le lisebelisoa ka botebo.
Sebopeho sa hydroxypropyl methylcellulose:
HPMC e tsoa ho cellulose, polima ea tlhaho e fumanehang maboteng a lisele tsa semela. Phetoho ea selulose e kenyelletsa ho kenngoa ha lihlopha tsa hydroxypropyl le methyl mokokotlong oa cellulose. Phetoho ena e fetola thepa ea polymer, e fana ka thepa e khethehileng e molemo bakeng sa mefuta e mengata ea likopo.
Hydrophilicity ea HPMC:
Hydroxy:
HPMC e na le dihlopha tsa hydroxypropyl mme ke hydrophilic. Lihlopha tsena tsa hydroxyl li na le kamano e phahameng ea limolek'hule tsa metsi ka lebaka la ho kopana ha haedrojene.
Sehlopha sa Hydroxypropyl se ka theha likamano tsa haedrojene ka limolek'hule tsa metsi, ho etsa hore HPMC e qhibilihe ka metsing ho isa tekanyong e itseng.
methyl:
Le hoja sehlopha sa methyl se kenya letsoho ho hydrophobicity ka kakaretso ea molek'hule, ha e hanyetsane le hydrophilicity ea sehlopha sa hydroxypropyl.
Sehlopha sa methyl ha se na polar, empa boteng ba sehlopha sa hydroxypropyl bo khetholla sebopeho sa hydrophilic.
Hydrophobicity ea HPMC:
methyl:
Lihlopha tsa methyl ho HPMC li fumana ho isa bohōleng bo itseng hydrophobicity ea eona.
Leha e se joalo ka hydrophobic joalo ka lipolima tse ling tse entsoeng ka botlalo, boteng ba lihlopha tsa methyl bo fokotsa hydrophilicity ka kakaretso ea HPMC.
Litšobotsi tsa ho etsa lifilimi:
HPMC e tsebahala ka thepa ea eona ea ho etsa lifilimi, 'me hangata e sebelisoa hampe litlhare le litlolo. Hydrophobicity e kenya letsoho ho thehoeng ha filimi e sireletsang.
Litšebelisano le lintho tse seng polar:
Lits'ebetsong tse ling, HPMC e ka sebelisana le lintho tse seng polar ka lebaka la hydrophobicity ea eona e sa fellang. Thepa ena e bohlokoa bakeng sa lits'ebetso tsa phano ea lithethefatsi indastering ea meriana.
Lisebelisoa tsa HPMC:
lithethefatsi:
HPMC e sebelisoa haholo mekhoeng ea meriana e le setlamo, sa pele sa filimi, le se feto-fetohang sa viscosity. Bokhoni ba eona ba ho etsa lifilimi bo thusa ho lokolloa ha lithethefatsi ka tsela e laoloang.
E sebelisoa mefuteng ea litekanyetso tse tiileng tsa molomo joalo ka matlapa le li-capsules.
Indasteri ea kaho:
Lefapheng la kaho, HPMC e sebelisoa lihlahisoa tse thehiloeng ho samente ho ntlafatsa ts'ebetso, ho boloka metsi le ho khomarela.
Hydrophilicity e thusa ho boloka metsi, ha hydrophobicity e thusa ho ntlafatsa ho khomarela.
indasteri ea lijo:
HPMC e sebelisoa e le setei se teteaneng le se etsang gelling indastering ea lijo. Sebopeho sa eona sa hydrophilic se thusa ho theha li-gel tse tsitsitseng le ho laola viscosity ea lihlahisoa tsa lijo.
cosmetic:
Ka litlolo tsa litlolo, HPMC e sebelisoa lihlahisoa tse kang litlolo le litlolo ka lebaka la thepa ea eona ea ho etsa lifilimi le ho tenya.
Hydrophilicity e netefatsa hore letlalo le na le metsi hantle.
ha re phethela:
HPMC ke polima hore ke ka bobeli hydrophilic le hydrophobic. Tekanyo lipakeng tsa hydroxypropyl le lihlopha tsa methyl sebopeho sa eona e e fa matla a ikhethang, a e lumellang ho ba le mefuta e mengata ea lits'ebetso. Ho utloisisa thepa ena ho bohlokoa bakeng sa ho loants'a HPMC ts'ebelisong e ikhethileng indastering e fapaneng, moo bokhoni ba HPMC ba ho sebelisana le metsi le lintho tse seng polar bo sebelisetsoa merero e fapaneng.
Nako ea poso: Dec-15-2023