Na carboxymethylcellulose FDA e amohetsoe?

Carboxymethylcellulose (CMC) ke motsoako o feto-fetohang o sebelisoang haholo liindastering tse fapaneng, ho kenyeletsoa lijo, meriana, litlolo le tlhahiso. Mehaho ea eona e nang le mesebetsi e mengata e etsa hore e be ea bohlokoa e le ntho e teteaneng, stabilizer, emulsifier le tse ling. Tsamaiso ea Lijo le Lithethefatsi ea United States (FDA) e bapala karolo ea bohlokoa ho laola polokeho le ts'ebeliso ea metsoako e joalo, ho netefatsa hore e fihlela litekanyetso tse thata pele e lumelloa ho sebelisoa lihlahisoa tsa bareki.

Ho utloisisa Carboxymethylcellulose (CMC)
Carboxymethylcellulose, eo hangata e khutsufatsoang joalo ka CMC, e tsoa ho selulose. Cellulose ke motsoako o mongata ka ho fetisisa oa lintho tse phelang Lefatšeng 'me o fumaneha marakong a lisele tsa limela, ho fana ka tšehetso ea sebopeho. CMC e tsoa ho selulose ka ts'ebetso ea phetoho ea lik'hemik'hale e kenyelletsang ho hlahisa lihlopha tsa carboxymethyl mokokotlong oa cellulose. Phetoho ena e fana ka lisebelisoa tse 'maloa tsa bohlokoa ho CMC, ho kenyelletsa ho qhibiliha ha metsi, viscosity, le botsitso.

Lintho tse molemo tsa Carboxymethylcellulose:
Ho qhibiliha ha Metsi: CMC e qhibiliha ka metsing, e etsa tharollo e hlakileng, e hlakileng. Thepa ena e etsa hore e be molemo lits'ebetsong tse fapaneng moo ho hlokahalang moemeli oa ho tiisa kapa oa ho tsitsisa.

Viscosity: CMC e bonts'a boitšoaro ba pseudoplastic, ho bolelang hore viscosity ea eona e fokotseha tlas'a khatello ea ho kuta 'me e eketseha hape ha khatello ea kelello e tlosoa. Thepa ena e lumella ts'ebeliso e bonolo lits'ebetsong tse joalo ka ho pompa, ho fafatsa, kapa extrusion.

Botsitso: CMC e fana ka botsitso ho li-emulsion le ho emisoa, ho thibela metsoako ho arohana kapa ho lula ka nako. Botsitso bona bo bohlokoa lihlahisoa tse kang liaparo tsa salate, litlolo, le ho emisoa ha meriana.

Ho Etsa Lifilimi: CMC e ka etsa lifilimi tse tšesaane, tse tenyetsehang ha li omisitsoe, tsa etsa hore e be molemo lits'ebetsong tse kang liphahlo tse jeoang tsa matlapa kapa li-capsules, le tlhahisong ea lifilimi bakeng sa thepa ea ho paka.

Lisebelisoa tsa Carboxymethylcellulose
CMC e fumana ts'ebeliso e atileng liindastering tse fapaneng ka lebaka la thepa ea eona e fapaneng. Lisebelisoa tse ling tse tloaelehileng li kenyelletsa:

Indasteri ea Lijo: CMC e sebelisoa e le setei, se tsitsisa, le se tlamang lihlahisoa tse ngata tsa lijo, ho kenyeletsoa li-sauces, li-dressings, ice cream, lintho tsa ho baka le lino. E thusa ho ntlafatsa sebopeho, molomo, le botsitso ba sethala.

Meriana ea Meriana: Litlhare, CMC e sebelisoa e le tlamahano ho metsoako ea matlapa, e teteaneng ka ho fanyeha, le e tsitsitseng ho emulsions. E netefatsa kabo e tšoanang ea lithethefatsi le ho matlafatsa boitlamo ba mokuli.

Litlolo le Lihlahisoa tsa Tlhokomelo ea Motho: CMC e sebelisoa ho litlolo le lihlahisoa tsa tlhokomelo ea botho tse kang litlolo, litlolo, li-shampoo, le sesepa sa meno e le setenya, emulsifier, le stabilizer. E thusa ho boloka botsitso ba sehlahisoa le ho ntlafatsa ts'ebetso.

Lisebelisoa tsa Indasteri: CMC e sebelisoa lits'ebetsong tse fapaneng tsa indasteri e le setei, se bolokang metsi, le se fetolang rheology lihlahisoa tse joalo ka litlolo, lipente, likhomaretsi le maro a chekang.

Ts'ebetso ea tumello ea FDA
United States, FDA e laola tšebeliso ea li-additives tsa lijo, ho kenyelletsa le lintho tse kang CMC, tlas'a Federal Food, Drug, and Cosmetic Act (FD&C Act) le Food Additives Amendment ea 1958. Taba ea mantlha ea FDA ke ho netefatsa hore lintho li teng. tse kentsoeng lijong li bolokehile hore li ka jeoa 'me li na le morero oa bohlokoa.

Ts'ebetso ea tumello ea FDA bakeng sa li-additives tsa lijo hangata e kenyelletsa mehato e latelang:

Tekolo ea Tšireletseho: Moetsi kapa mofani oa motsoako oa lijo o ikarabella bakeng sa ho etsa lithuto tsa polokeho ho bontša hore ntho eo e bolokehile bakeng sa tšebeliso e reriloeng. Lithuto tsena li kenyelletsa liteko tsa toxicological, lithuto tsa metabolism, le allergenicity e ka bang teng.

Tlhahiso ea Kopo ea Keketso ea Lijo: Moetsi o fana ka kopo ea tlatsetso ea lijo (FAP) ho FDA, e fana ka tlhaiso-leseling e felletseng mabapi le boitsebahatso, sebopeho, ts'ebetso ea tlhahiso, ts'ebeliso e reriloeng, le data ea polokeho ea sehokelo. Kopo e boetse e tlameha ho kenyelletsa litlhoko tse sisintsoeng tsa ho ngolisoa.

Tlhahlobo ea FDA: FDA e lekola lintlha tsa polokeho tse fanoeng ho FAP ho fumana hore na tlatsetso e bolokehile bakeng sa tšebeliso e reriloeng tlas'a maemo a ts'ebeliso a boletsoeng ke mokopi. Tlhahlobo ena e kenyelletsa tlhahlobo ea likotsi tse ka bang teng bophelong ba batho, ho kenyeletsoa maemo a ho pepeseha le litlamorao life kapa life tse tsejoang tse mpe.

Phatlalatso ea Melao e Reriloeng: Haeba FDA e etsa qeto ea hore tlatsetso e bolokehile, e phatlalatsa molao o reriloeng ho Federal Register, e totobatsang maemo ao tlatsetso e ka sebelisoang lijong. Sengoliloeng sena se lumella sechaba ho fana ka maikutlo le maikutlo ho tsoa ho ba amehang.

Melao ea ho Qetela: Ka mor'a ho nahana ka litlhaloso tsa sechaba le lintlha tse eketsehileng, FDA e fana ka molao oa ho qetela oa ho lumella kapa ho hana tšebeliso ea lijo tse kenyelletsoeng lijong. Haeba e amohetsoe, molao oa ho qetela o theha maemo a lumelletsoeng a ts'ebeliso, ho kenyeletsoa mefokolo leha e le efe, litlhaloso, kapa litlhoko tsa ho ngola.

Carboxymethylcellulose le Tumello ea FDA
Carboxymethylcellulose e na le nalane ea tšebeliso indastering ea lijo le makaleng a mang, 'me ka kakaretso e amoheloa e le e bolokehileng (GRAS) bakeng sa ts'ebeliso ea eona e reriloeng ha e sebelisoa ho latela mekhoa e metle ea tlhahiso. FDA e fane ka melao le litataiso tse tobileng tse laolang tšebeliso ea CMC lijong le lihlahisoa tsa meriana.

Taolo ea FDA ea Carboxymethylcellulose:
Boemo ba Keketso ea Lijo: Carboxymethylcellulose e thathamisitsoe e le tlatsetso ea lijo e lumelletsoeng ho Sehlooho sa 21 sa Khoutu ea Melao ea Naha (CFR) tlas'a karolo ea 172.Code 8672, e nang le melao e tobileng e hlalositsoeng bakeng sa tšebeliso ea eona likarolong tse fapaneng tsa lijo. Melao ena e hlakisa maemo a phahameng a lumelletsoeng a CMC lihlahisoa tse fapaneng tsa lijo le litlhoko tse ling tse amehang.

Tšebeliso ea Litlhare: Litlhareng tsa meriana, CMC e sebelisoa e le motsoako o sa sebetseng oa metsoako ea lithethefatsi, 'me tšebeliso ea eona e laoloa tlas'a Setsi sa FDA sa Tlhahlobo le Lipatlisiso tsa Lithethefatsi (CDER). Baetsi ba tlameha ho etsa bonnete ba hore CMC e kopana le litlhaloso tse boletsoeng United States Pharmacopeia (USP) kapa compendia e 'ngoe e amehang.

Litlhoko tsa ho Laela: Lihlahisoa tse nang le CMC joalo ka motsoako li tlameha ho latela melaoana ea FDA mabapi le ho ngola, ho kenyeletsoa lethathamo le nepahetseng la metsoako le mongolo ofe kapa ofe o hlokahalang oa allergen.

Carboxymethylcellulose (CMC) ke motsoako o sebelisoang haholo o nang le lits'ebetso tse fapaneng indastering ea lijo, ea meriana, ea litlolo le ea tlhahiso. Litšobotsi tsa eona tse ikhethang li etsa hore e be ea bohlokoa joalo ka motenya, stabilizer, emulsifier le binder lihlahisoa tse fapaneng. FDA e bapala karolo ea bohlokoa ho laola polokeho le ts'ebeliso ea CMC le litlatsetso tse ling tsa lijo, ho netefatsa hore li fihlela litekanyetso tse matla tsa polokeho pele li lumeloa hore li sebelisoe lihlahisoa tsa bareki. CMC e thathamisitsoe e le tlatsetso ea lijo e lumelletsoeng ke FDA, 'me ts'ebeliso ea eona e laoloa ke melaoana le litataiso tse boletsoeng ho Sehlooho sa 21 sa Khoutu ea Melao ea Naha. Baetsi le barekisi ba lihlahisoa tse nang le CMC ba tlameha ho latela melaoana ena, ho kenyeletsoa litekanyetso tsa polokeho, litlhoko tsa ho ngola, le maemo a ts'ebeliso a boletsoeng, ho netefatsa polokeho le boleng ba lihlahisoa tsa bona.