Hydroxypropylmethylcellulose (HPMC) ke cellulose ether e sebelisoang haholo liindastering tse fapaneng ka lebaka la thepa ea eona e ikhethang le ho ikamahanya le maemo. Ke polima e se nang chefo, e qhibilihang ka metsing e qhibilihang metsing a batang le a chesang. Ke thepa ea bohlokoa e tala e 'nileng ea sebelisoa e le setenya, se tlamang, se tsitsitseng, se emulsifier, le filimi ea pele lits'ebetsong tse fapaneng tse kang indasteri ea lijo, meriana, kaho le litlolo.
E 'ngoe ea thepa ea mantlha ea HPMC ke mefuta ea eona e pharalletseng ea viscosity. The viscosity ea HPMC itšetlehile ka lintlha tse 'maloa tse kang tekanyo ea ho fetola, boima ba limolek'hule le mahloriso. Ka hona, HPMC e ka sebelisoa lits'ebetsong tse fapaneng tse hlokang maemo a fapaneng a viscosity. Ka mohlala, HPMC e nang le viscosity e phahameng e atisa ho sebelisoa e le setsi se matla le se tsitsitseng lijong, ha HPMC e nang le viscosity e tlaase e sebelisoa indastering ea meriana e le sekontiri le ho roala letlapa.
HPMC bohloeki e boetse ke ntlha ea bohlokoa. Hangata e tla ka limaraka tse fapaneng tsa bohloeki ho tloha ho 99% ho isa ho 99.9%. Limaraka tse phahameng ka ho fetisisa tsa bohloeki hangata li ratoa ke indasteri ea meriana, e nang le melao e thata ea boleng ba lisebelisoa tse tala. Bohloeki bo phahameng ba HPMC bo thusa ho netefatsa boleng bo botle ba sehlahisoa sa ho qetela. Boemo ba bohloeki bo boetse bo ama thepa ea HPMC joalo ka viscosity, solubility, le gelation. Ka kakaretso, maemo a phahameng a bohloeki a ntlafatsa litšobotsi tsa ts'ebetso.
Ho phaella ho viscosity le bohloeki, ho na le lintlha tse ling tsa bohlokoa tseo u ka li nahanang ha u khetha HPMC e nepahetseng bakeng sa kopo e itseng. Tsena li kenyelletsa boholo ba likaroloana, sebaka se ka holimo, mongobo le tekanyo ea ho fetola. Boholo ba likaroloana le bokaholimo ba HPMC bo ka ama ho qhibiliha ha eona, ha mongobo o ama botsitso le bophelo ba eona. Ho bohlokoa ho khetha tekanyo e nepahetseng ea ho kenya sebaka, ke hore, karolo e lekanyelitsoeng ea hydroxypropyl le li-methyl substituents ho molek'hule ea HPMC. Likhato tse phahameng tsa ho nka sebaka li ka lebisa ho qhibiliheng ha metsi ho eketsehileng le ho ntlafatsa viscosity, ha likhato tse tlase tsa ho nka sebaka li ka lebisa ho ntlafatso ea thepa ea ho etsa lifilimi.
indasteri ea lijo
Indastering ea lijo, HPMC e atisa ho sebelisoa e le setenya, emulsifier le stabilizer lihlahisoa tse fapaneng tse kang li-sauces, sopho, liaparo, lihlahisoa tsa lebese le thepa e halikiloeng. HPMC e ntlafatsa sebopeho sa lijo ka ho fana ka sebopeho se boreleli, se monate le se ts'oanang. E boetse e thusa ho thibela metsoako ho arohana, kahoo e lelefatsa bophelo ba lishelefo ea lijo.
E 'ngoe ea litšobotsi tsa mantlha tsa HPMC indastering ea lijo ke bokhoni ba eona ba ho boloka viscosity ea sehlahisoa maemong a phahameng a mocheso, joalo ka nakong ea ho pheha le ho pasteurization. Botsitso bo phahameng ba mocheso oa HPMC bo e lumella hore e sebelisoe lijong tse nang le mocheso o phahameng joalo ka lihlahisoa tse entsoeng ka makotikoting kapa tse tsitsitseng.
Indasteri ea meriana
Ka indasteri ea meriana, HPMC e atisa ho sebelisoa e le binder, disintegrant, tablet coating agent, controlled release agent, joalo-joalo litokisetsong tse fapaneng tsa meriana. HPMC e ratoa ho feta likhomaretsi tse ling hobane ha e chefo ebile e qhibiliha metsing a chesang le a batang. Bokhoni ba ho qhibiliha metsing a chesang le a batang bo bohlokoa ka ho khetheha bakeng sa granulation e metsi, mokhoa o tloaelehileng oa ho hlahisa matlapa.
HPMC e boetse e sebelisoa e le disintegrant bakeng sa matlapa. E thusa ho pshatla lipilisi ka likotoana tse nyane, e leng ho ntlafatsang lebelo leo moriana o kenang 'meleng ka lona. Ho phaella moo, HPMC e atisa ho sebelisoa e le moemeli oa ho roala ka lebaka la thepa ea eona ea ho etsa lifilimi. E sireletsa letlapa ho tloha linthong tsa tikoloho, kahoo e lelefatsa bophelo ba sethala.
mamella
Indastering ea kaho, HPMC e sebelisoa ho ntlafatsa ts'ebetso le ts'ebetso ea lihlahisoa tse fapaneng tsa samente tse kang seretse, li-grouts le plaster. HPMC e sebetsa joalo ka motenya, e ntlafatsa ho khomarela, 'me e fana ka thepa ea ho boloka metsi ho motsoako. Bokhoni ba HPMC ba ho etsa filimi e sireletsang le bona bo thusa ho thibela metsi ho kenella ka har'a matrix a samente, ho ntlafatsa ho tšoarella. Viscosity ea HPMC e bapala karolo ea bohlokoa ts'ebetsong ea motsoako. Ka hona, ho latela ts'ebeliso, limaraka tse fapaneng tsa viscosity tsa HPMC lia sebelisoa.
setlolo
Indastering ea litlolo, HPMC e sebelisoa e le setei, se tsitsitseng, le filimi ea pele lihlahisoa tse fapaneng tse kang li-shampoo, li-conditioner le litlolo. HPMC e ntlafatsa sebopeho le botsitso ba litlolo, e fana ka pheletso e boreleli, e monate. E boetse e ntlafatsa botsitso ba sehlahisoa le bophelo ba sethala ka ho thibela ho arohana ha metsoako. Ho feta moo, thepa ea ho etsa filimi ea HPMC e fana ka thibelo e sireletsang e thusang ho boloka mongobo, kahoo e thibela ho omella.
ha re phethela
Hydroxypropyl methylcellulose e na le mefuta e mengata ea viscosity le litlhoko tsa bohloeki. Ke thepa e tala e nang le mesebetsi e mengata e sebelisoang haholo liindastering tse fapaneng tse kang lijo, meriana, kaho le litlolo. Sebaka se pharaletseng sa viscosity se lumella HPMC ho sebelisoa lits'ebetsong tse fapaneng tse hlokang maemo a fapaneng a viscosity. Boemo bo phahameng ba bohloeki bo bohlokoa haholo indastering ea meriana, e nang le melao e thata ea boleng ba lisebelisoa tse tala. HPMC e bohlokoa haholo ts'ebetsong ea lihlahisoa tse ngata, ka hona ho bohlokoa ho ela hloko viscosity e nepahetseng le boemo ba bohloeki.
Nako ea poso: Sep-06-2023