Mokhoa oa ho sebelisa hydroxypropyl methylcellulose?

Hydroxypropyl methylcellulose (HPMC) ke motsoako o feto-fetohang le o sebelisoang haholo ho kenyelletsa meriana, kaho, lijo le litlolo. Ke motsoako oa cellulose o bonts'ang mefuta e mengata ea thepa e etsang hore e be ea bohlokoa bakeng sa lits'ebetso tse fapaneng.

1. Selelekela sa Hydroxypropyl Methylcellulose (HPMC)

1.1 Tlhaloso le sebopeho

Hydroxypropylmethylcellulose (HPMC) ke semi-synthetic polymer e nkiloeng ho selulose. E hlahisoa ka ho fetola selulose ka ho eketsoa ha lihlopha tsa propylene glycol le methoxy. Polymer e hlahisoang e na le hydroxypropyl le methoxy substituents mokokotlong oa cellulose.

1.2 Mokhoa oa tlhahiso

HPMC hangata e hlahisoa ka ho phekola selulose ka motsoako oa propane oxide le methyl methyl chloride. Ts'ebetso ena e fella ka li-polymers tse ngata tse nang le thepa e ikhethang, ho kenyelletsa le ho ntlafatsa ho qhibiliha ha metsi le botsitso ba mocheso.

2. Lintho tsa 'mele le tsa lik'hemik'hale tsa HPMC

2.1 Solubility

E 'ngoe ea litšobotsi tse hlokomelehang tsa HPMC ke ho qhibiliha ha eona metsing. Tekanyo ea ho qhibiliha e itšetlehile ka, mohlala, tekanyo ea ho fetola le tekanyo ea boima ba molek'hule. Sena se etsa hore HPMC e be motsoako oa bohlokoa mefuteng e fapaneng ea libopeho tse hlokang tokollo e laoloang e fetotsoeng kapa phetoho ea viscosity.

2.2 Ho tsitsa ha mocheso

HPMC e bonts'a botsitso bo botle ba mocheso, e etsa hore e loketse lits'ebetso moo ho hanyetsa mocheso ho leng bohlokoa. Thepa ena e bohlokoa haholo indastering ea kaho, moo HPMC e sebelisoang ka thepa ea samente ho ntlafatsa ts'ebetso le ts'ebetso.

2.3 Thepa ea mali

Thepa ea rheological ea HPMC e kenya letsoho katlehong ea eona ea ho laola ho phalla le ho tsitsa ha metsoako. E ka sebetsa e le motenya, e fana ka taolo ea viscosity ka har'a litsamaiso tse nang le metsi le tse se nang metsi.

3. Tšebeliso ea hydroxypropyl methylcellulose

3.1 Indasteri ea meriana

Indastering ea meriana, HPMC e sebelisoa haholo ha ho etsoa liforomo tsa litekanyetso tse tiileng tsa molomo, ho kenyeletsoa matlapa le li-capsules. E na le mesebetsi e mengata e kang binder, e arolang le e laoloang ea tokollo.

3.2Indasteri ea kaho

HPMC e sebelisoa haholo lebaleng la kaho e le tlatsetso ea thepa e thehiloeng ho samente. E ntlafatsa ho boloka metsi, ho sebetsa le ho khomarela, ho etsa hore e be karolo ea bohlokoa ka har'a seretse, sekhomaretsi sa lithaele le metsoako ea ho intlafatsa.

3.3 Indasteri ea lijo

Ka indasteri ea lijo, HPMC e sebelisoa e le setenya, se tsitsitseng le emulsifier. Hangata e sebelisoa lihlahisoa tsa lebese, li-sauces le lintho tse halikiloeng ho ntlafatsa sebopeho le molomo.

3.4 Indasteri ea Botle

Indasteri ea litlolo e sebelisa HPMC ka mefuta e fapaneng ea litlolo, ho kenyeletsoa litlolo, litlolo le li-shampoo. E kenya letsoho ho viscosity le botsitso ba litlolo, ka hona ho ntlafatsa ts'ebetso ea bona ka kakaretso.

4. Mokhoa oa ho sebelisa hydroxypropyl methylcellulose

4.1 Ho kenyeletsoa mefuteng ea meriana

Ka metsoako ea meriana, HPMC e ka kenyelletsoa nakong ea lehlabathe kapa ts'ebetso ea khatello. Khetho ea kereiti le mahloriso e ipapisitse le boemo bo lakatsehang ba tokollo le thepa ea mochini ea foromo ea ho qetela ea litekanyetso.

4.2 Kopo ea kaho

Bakeng sa lits'ebetso tsa kaho, HPMC hangata e eketsoa ho metsoako e omileng, joalo ka samente kapa lihlahisoa tse thehiloeng ho gypsum. Phatlalatso e nepahetseng le ho kopanya ho netefatsa hore ho tšoana le litekanyetso li lokisoa ho latela litlhoko tse khethehileng tsa kopo.

4.3 Maikemisetso a ho pheha

Lits'ebetsong tsa ho pheha, HPMC e ka qhalakanngoa ka metsing kapa ka lino tse ling ho theha sebopeho se ts'oanang sa gel. Ho bohlokoa ho latela maemo a khothaletsoang a ts'ebeliso ho fihlela sebopeho se lakatsehang lihlahisoa tsa lijo.

4.4 Mekhoa ea botle

Ka litlolo tsa litlolo, HPMC e eketsoa nakong ea emulsification kapa sethaleng sa thickening. Phatlalatso e nepahetseng le ho kopanya ho netefatsa kabo e ts'oanang ea HPMC, ka hona ho kenya letsoho botsitsong le botsoakong ba sehlahisoa sa ho qetela.

5. Litlhokomelo le Litlhokomelo

5.1 Ho lumellana le lisebelisoa tse ling

Ha ho etsoa le HPMC, ho lumellana ha eona le lisebelisoa tse ling ho tlameha ho nahanoa. Lintho tse ling li ka sebelisana le HPMC, tsa ama mohopolo oa eona kapa botsitso mokhoeng oa eona o phethahetseng.

5.2 Polokelo le bophelo ba shelofo

HPMC e lokela ho bolokoa sebakeng se phodileng, se omileng ho thibela ho senyeha. Tlhokomelo e lokela ho nkoa ho qoba ho pepesehela mocheso o feteletseng kapa mongobo. Ho feta moo, bahlahisi ba tlameha ho latela litataiso tse khothaletsoang tsa bophelo ba lishelefo ho netefatsa boleng ba sehlahisoa.

5.3 Mehato ea tšireletso

Leha HPMC ka kakaretso e nkuoa e bolokehile hore e ka sebelisoa lits'ebetsong tse fapaneng, litataiso tsa polokeho le likhothaletso tse fanoeng ke moetsi li tlameha ho lateloa. Lisebelisoa tsa ts'ireletso tse kang liatlana le likhalase li lokela ho sebelisoa ha u sebetsana le litharollo tse tsepamisitsoeng tsa HPMC.

Hydroxypropyl methylcellulose (HPMC) ke polymer e feto-fetohang le ea bohlokoa e sebelisoang haholo ho tsa meriana, kaho, lijong le litlolong. Ho bohlokoa ho utloisisa litšobotsi tsa eona le tšebeliso e nepahetseng bakeng sa baetsi ba liindasteri tse fapaneng. Ka ho latela litataiso tse khothalelitsoeng le lintlha tse kang ho solubility, ho lumellana, le mehato ea ts'ireletso, HPMC e ka sebelisoa ka nepo ho ntlafatsa ts'ebetso ea lihlahisoa tse fapaneng le litlolo.