Hydroxypropyl methylcellulose (HPMC) ke polymer e nkiloeng ho selulose 'me e sebelisoa hangata liindastering tse fapaneng, ho kenyeletsoa meriana, litlolo le lijo.Ke polima e qhibilihang ka metsing e ka tšelisoang habonolo ho etsa tharollo ea viscous.
1. Ho utloisisa HPMC:
Pele o bua ka ts'ebetso ea hydration, ho bohlokoa ho utloisisa thepa ea HPMC.HPMC ke semi-synthetic polymer e leng hydrophilic, ho bolelang hore e na le kamano e matla ea metsi.E etsa li-gel tse pepeneneng, tse tenyetsehang, le tse tsitsitseng ha li na le metsi, e leng se etsang hore e tšoanelehe bakeng sa mefuta e mengata ea likopo.
2. Ts'ebetso ea Hydration:
The hydration ea HPMC e kenyelletsa ho qhala phofo ea polymer ka metsing le ho e lumella hore e ruruhe ho etsa tharollo ea viscous kapa gel.Mona ke tataiso ea mohato ka mohato ho hydrating HPMC:
Khetha Kereiti e Nepahetseng:
HPMC e fumaneha ka limaraka tse fapaneng ka boima bo fapaneng ba limolek'hule le limaraka tsa viscosity.Khetho ea sehlopha se loketseng e itšetlehile ka viscosity e lakatsehang ea tharollo ea ho qetela kapa gel.Limaraka tse phahameng tsa boima ba limolek'hule ka kakaretso li fella ka tharollo e phahameng ea viscosity.
Lokisa Metsi:
Sebelisa metsi a hloekisitsoeng kapa a hloekisitsoeng bakeng sa hydrating HPMC ho netefatsa ho ba sieo ha litšila tse ka amang thepa ea tharollo.Mocheso oa metsi o ka boela oa ama ts'ebetso ea hydration.Ka kakaretso, ho sebelisa metsi a mocheso oa kamore ho lekane, empa ho futhumatsa metsi hanyenyane ho ka potlakisa ts'ebetso ea hydration.
Phatlalatso:
Butle-butle u fafatse phofo ea HPMC ka metsing ha u ntse u susumetsa ka mokhoa o tsoelang pele ho thibela ho thehoa ha li-clumps.Ho bohlokoa ho eketsa polymer butle-butle ho netefatsa phallo e ts'oanang le ho thibela ho kopana.
Hydration:
Tsoela pele ho susumetsa motsoako ho fihlela phofo eohle ea HPMC e hasane ka metsing.Lumella motsoako hore o eme nako e lekaneng ho lumella likaroloana tsa polymer hore li ruruhe le ho nosetsa ka botlalo.Nako ea hydration e ka fapana ho latela lintlha tse kang mocheso, polymer grade, le viscosity e lakatsehang.
Ho kopanya le Homogenization:
Ka mor'a nako ea hydration, kopanya tharollo ka botlalo ho netefatsa ho tšoana.Ho itšetlehile ka kopo, ho kopanya ho eketsehileng kapa homogenization ho ka 'na ha hlokahala ho finyella tumellano e lakatsehang le ho felisa maqeba leha e le afe a setseng.
Ho fetola pH le Additives (haeba ho hlokahala):
Ho ipapisitse le ts'ebeliso e ikhethileng, ho ka 'na ha hlokahala hore u fetole pH ea tharollo u sebelisa li-acids kapa li-bases.Ho feta moo, li-additives tse ling tse kang li-preservatives, plasticizers, kapa thickeners li ka kenyelletsoa tharollo sethaleng sena ho ntlafatsa ts'ebetso ea eona kapa botsitso.
Sefa (haeba ho hlokahala):
Maemong a mang, haholo-holo lits'ebetsong tsa meriana kapa tsa litlolo, ho hloekisa tharollo ea hydrated ho ka 'na ha hlokahala ho tlosa likaroloana leha e le life tse sa tsitsang kapa litšila, ho fella ka sehlahisoa se hlakileng le se ts'oanang.
3. Likopo tsa Hydrated HPMC:
Hydrated HPMC e fumana lits'ebetso liindastering tse fapaneng:
- Indasteri ea Meriana: Mekhahlelong ea meriana, HPMC e nang le hydrated e sebelisoa e le sekontiri se teteaneng, se tlamang, le se etsang filimi ka har'a litlolo tsa letlapa.
- Indasteri ea Litlolo: HPMC e atisa ho sebelisoa lihlahisoa tsa litlolo tse kang litlolo, litlolo, le li-gel e le ntho e teteaneng, e tsitsitseng le e etsang lifilimi.
- Indasteri ea Lijo: Indastering ea lijo, HPMC e nang le hydrate e sebelisoa e le setenya, emulsifier, le stabilizer lihlahisoa tse kang lisoso, liaparo le lihlahisoa tsa lebese.
- Indasteri ea Kaho: HPMC e sebelisoa linthong tsa kaho tse kang seretse, li-grouts, le likhomaretsi tsa lithaele ho ntlafatsa ts'ebetso, ho boloka metsi le ho khomarela.
4. Qetello:
Hydroxypropyl methylcellulose (HPMC) ke polima e nang le mefuta e mengata e ka tšelisoang habonolo ho etsa litharollo tsa viscous kapa li-gel.Ts'ebetso ea hydration e kenyelletsa ho qhalakanya phofo ea HPMC ka metsing, ho e lumella hore e ruruhe, le ho kopanya ho finyella ts'ebetso e ts'oanang.Hydrated HPMC e fumana lits'ebetso liindastering tse fapaneng, ho kenyeletsoa tsa meriana, litlolo, lijo le kaho.Ho utloisisa ts'ebetso ea hydration le thepa ea HPMC ke ea bohlokoa bakeng sa ho ntlafatsa ts'ebetso ea eona lits'ebetsong tse fapaneng.
Nako ea poso: Mar-19-2024