Hypromellose e etsoa joang?

Hypromellose, eo hape e tsejoang e le hydroxypropyl methylcellulose (HPMC), ke polymer ea semisynthetic e nkiloeng ho cellulose, polysaccharide ea tlhaho e fumanehang maboteng a lisele tsa semela. Tlhahiso ea hypromellose e kenyelletsa mehato e mengata, ho kenyelletsa le etherification le tlhoekiso. Mona ke kakaretso ea hore na hypromellose e etsoa joang:

1. Cellulose Sourcing: Ts'ebetso e qala ka ho fumana selulose, e ka fumanoang mehloling e fapaneng ea limela joalo ka makhasi a patsi, likhoele tsa k'hothone kapa limela tse ling tse nang le fiber. Cellulose hangata e ntšoa mehloling ena ka letoto la lits'ebetso tsa lik'hemik'hale le tsa mochini ho fumana thepa e hloekisitsoeng ea cellulose.
2. Etherification: Selulose e hloekisitsoeng e kena ts'ebetsong ea phetoho ea lik'hemik'hale e bitsoang etherification, moo lihlopha tsa hydroxypropyl le methyl li kenngoa mokokotlong oa cellulose. Phetoho ena e finyelloa ka ho sebetsana le cellulose ka propylene oxide (ho hlahisa lihlopha tsa hydroxypropyl) le methyl chloride (ho hlahisa lihlopha tsa methyl) tlas'a maemo a laoloang.
3. Ho hloeka: Ka mor'a hore etherification, sehlahisoa se hlahisoang se hloekisoa ho tlosa litšila le lihlahisoa tse tsoang karabelong. Sena se ka kenyelletsa ho hlatsoa, ​​ho sefa, le mekhoa e meng ea karohano ho fumana sehlahisoa se hloekileng sa hypromellose.
4. Ho omisa le ho sila: Hypromellose e hloekisitsoeng e ntan'o omisoa ho tlosa mongobo o feteletseng 'me e siloa ka phofo e ntle kapa granules. Boholo ba likaroloana le morphology ea phofo ea hypromellose e ka laoloa ho finyella litlhoko tse khethehileng bakeng sa likopo tse fapaneng.
5. Taolo ea Boleng: Nakong eohle ea ts'ebetso ea tlhahiso, mehato ea taolo ea boleng e sebelisoa ho netefatsa bohloeki, botsitso le ts'ebetso ea sehlahisoa sa hypromellose. Sena se kenyelletsa tlhahlobo ea liparamente tse kang boima ba limolek'hule, viscosity, solubility, le lisebelisoa tse ling tsa 'mele le tsa lik'hemik'hale.
6. Ho Paka le Kabo: Hang ha sehlahisoa sa hypromellose se kopana le litlhaloso tsa boleng, se pakoa ka lijaneng tse nepahetseng ebe se abeloa liindasteri tse fapaneng bakeng sa ho sebelisoa ho tsa meriana, lihlahisoa tsa lijo, litlolo le lits'ebetso tse ling.

Ka kakaretso, tlhahiso ea hypromellose e kenyelletsa letoto la karabelo ea lik'hemik'hale tse laoloang le mehato ea tlhoekiso e sebelisoang ho selulose, e hlahisang polymer e feto-fetohang le e sebelisoang haholo e nang le lits'ebetso tse fapaneng liindastering tse fapaneng.