HPMC ea Boleng bo Phahameng e Sebelisitsoeng Bakeng sa Sekhomaretsi sa Samente se Thehiloeng ka Tile Hydroxypropyl Methyl Cellulose HPMC
latela konteraka”, e tsamaellana le tlhokeho ea mmaraka, e kenelletseng nakong ea tlholisano ea mebaraka ka boleng ba eona bo holimo hape e fana ka litšebeletso tse felletseng le tse ikhethang bakeng sa bareki ho ba lumella ho fetoha bahloli ba bohlokoa. Ts'ebetso ea khoebo, ehlile ke khotsofalo ea bareki bakeng sa HPMC ea Boleng bo Phahameng e Sebelisitsoeng Bakeng sa Sekhomaretsi sa Lithaele sa Samente Hydroxypropyl Methyl Cellulose HPMC, Re tla leka ka matla ho boloka rekoto ea rona e ntle haholo re le mofani oa lihlahisoa tse ntlehali lefatšeng. Ha u na le lipotso kapa maikutlo, u lokela ho ikopanya le rona ka bolokolohi.
latela konteraka”, e tsamaellana le tlhokeho ea mmaraka, e kenelletseng nakong ea tlholisano ea mebaraka ka boleng ba eona bo holimo hape e fana ka litšebeletso tse felletseng le tse ikhethang bakeng sa bareki ho ba lumella ho fetoha bahloli ba bohlokoa. Ho phehella khoebo, ka sebele ke ho khotsofatsa bareki bakeng saChina HPMC le Hydroxypropyl Methyl Cellulose, Re na le makala a 48 a liprofinse ka har'a naha. Re boetse re na le tšebelisano-'moho e tsitsitseng le lik'hamphani tse 'maloa tsa machaba tsa khoebo. Ba re fa odara le ho romela litharollo linaheng tse ling. Re lebeletse ho sebelisana le uena ho hlahisa 'maraka o moholoanyane.
Tlhaloso ea Sehlahisoa
Hydroxypropyl Methyl Cellulose(HPMC)
Foromo ea limolek'hule
Hypromellose (Hydroxypropylmethylcellulose: HPMC) mofuta oa sebaka sa 2910, 2906, 2208 (USP)
Thepa ea 'Mele
- phofo e tšoeu kapa e mosehla
- E qhibiliha ka har'a motsoako oa organic kapa aqueous solvent
- Ho etsa filimi e bonaletsang ha solvent e tlosa
- Ha ho na karabelo ea lik'hemik'hale ka lithethefatsi ka lebaka la thepa ea eona e seng ea ionic
- Boima ba Limolek'hule : 10,000 ~ 1,000,000
- Ntlha ea gel: 40 ~ 90 ℃
- Sebaka sa ho khantša: 360 ℃
Hydroxypropyl Methylcellulose (HPMC) Pharmaceutical Grade ke Hypromellose pharmaceutical excipient and supplement, e ka sebelisoang e le thickener, dispersant, emulsifier and film-forming agent.
QualiCell Cellulose ether e na le methyl cellulose (USP, EP,BP,CP) le mefuta e meraro ea substitution ea hydroxypropyl methyl cellulose (hypromellose USP, EP,BP,CP) e 'ngoe le e 'ngoe e fumaneha ka mekhahlelo e mengata e fapaneng ka viscosity.Lihlahisoa tsa HPMC li nkiloe ho tlhaho e hloekisitsoeng lesela la k'hothone le makhasi a patsi, tse fihlelang litlhoko tsohle tsa USP, EP, BP, hammoho le Litifikeiti tsa Kosher le Halal.
Ha ho etsoa tlhahiso, k'hothone ea tlhaho e hloekisitsoeng haholo e etherified ka methyl chloride kapa ka motsoako oa methyl chloride le propylene oxide ho etsa ether e qhibilihang ka metsing, e seng ea ionic cellulose. Ha ho lisebelisoa tsa liphoofolo tse sebelisoang tlhahisong ea HPMC.HPMC e ka sebelisoang e le setlamo sa mefuta e tiileng ea litekanyetso tse kang matlapa le granules. E boetse e sebetsa ka mefuta e sa tšoaneng ea mesebetsi, ka mehlala, ho matlafatsa ho boloka metsi, ho teteaneng, ho sebetsa e le colloid e sireletsang ka lebaka la mosebetsi oa eona oa holim'a metsi, ho boloka ho lokolloa, le ho thehoa ha filimi.
QualiCell HPMC e fana ka mesebetsi e fapaneng e kang ho boloka metsi, colloid e sireletsang, ts'ebetso ea holim'a metsi, tokollo e tsitsitseng. Ke motsoako o seng oa ionic o hananang le ho tsoa letsoai le ho tsitsisa ho feta pH-range e pharaletseng. Lits'ebetso tse tloahelehileng tsa HPMC li tlamella liforomo tsa litekanyetso tse tiileng joalo ka matlapa le granules kapa thickener bakeng sa lits'ebetso tsa mokelikeli.
Pharma HPMC e tla ka mefuta e fapaneng ea viscosity ho tloha ho 3 ho isa ho 200,000 cps, 'me e ka sebelisoa haholo bakeng sa ho roala letlapa, granulation, binder, thickener, stabilizer le ho etsa capsule ea HPMC ea meroho.
Tlhaloso ea Lik'hemik'hale
Hypromellose Tlhaloso | 60E( 2910) | 65F( 2906) | 75K( 2208) |
Mocheso oa mocheso oa gel (℃) | 58-64 | 62-68 | 70-90 |
Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
Hydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
Viscosity(cps, 2% Tharollo) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000,100000,150000,200000 |
Sehlahisoa Kereiti
Hypromellose Tlhaloso | 60E( 2910) | 65F( 2906) | 75K( 2208) |
Mocheso oa mocheso oa gel (℃) | 58-64 | 62-68 | 70-90 |
Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
Hydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
Viscosity(cps, 2% Tharollo) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000,100000,150000,200000 |
Kopo
Pharma Grade HPMC e etsa hore ho be le mekhoa e laoloang ea tokollo ka boiketlo ba mochine o sebelisoang ka ho fetisisa oa ho tlama letlapa. Pharma Grade e fana ka phallo e ntle ea phofo, ho tšoana ha litaba, le ho hatelloa, ho etsa hore li tšoanelehe bakeng sa khatello e tobileng.
Kopo ea Pharma Excipients | Pharma Grade HPMC | Tekanyetso |
Bongata bo Laxative | 75K4000,75K100000 | 3-30% |
Litlolo, li-gel | 60E4000,75K4000 | 1-5% |
Boitokisetso ba Mahlo | 60E4000 | 01.-0.5% |
Litokisetso tsa Marotholi a Mahlo | 60E4000 | 0.1-0.5% |
Moemeli ea Emisang Mosebetsi | 60E4000, 75K4000 | 1-2% |
Li-antacids | 60E4000, 75K4000 | 1-2% |
Matlapa Binder | 60E5, 60E15 | 0.5-5% |
Kopano Metsi Granulation | 60E5, 60E15 | 2-6% |
Liaparo tsa Letlapa | 60E5, 60E15 | 0.5-5% |
Laola Release Matrix | 75K100000,75K15000 | 20-55% |
Likarolo le Melemo
- E ntlafatsa litšobotsi tsa phallo ea sehlahisoa
- E fokotsa nako ea ho sebetsa
- Liprofaele tse tšoanang, tse tsitsitseng tsa ho felisoa
- E ntlafatsa ho tšoana ha litaba
- E fokotsa litšenyehelo tsa tlhahiso
- E boloka matla a tsitsitseng ka mor'a ts'ebetso ea ho kopanya habeli (rolara compaction).
Sephutheloana
Pakete e tloaelehileng ke 25kg / moropa
20'FCL: lithane tse 9 tse nang le palletized; Lithane tse 10 tse sa phethoang.
40'FCL: lithane tse 18 tse nang le palletized; 20 ton unpalletized.ho latela konteraka”, e tsamaellana le tlhokahalo ea mmaraka, e kenela tlholisano ea 'maraka ka boleng ba eona bo holimo hape e fana ka litšebeletso tse felletseng le tse ikhethang bakeng sa bareki ho ba lumella ho fetoha bahloli ba bohlokoa. Ts'ebetso ea khoebo, ehlile ke khotsofalo ea bareki bakeng sa HPMC ea Boleng bo Phahameng e Sebelisitsoeng Bakeng sa Sekhomaretsi sa Lithaele sa Samente Hydroxypropyl Methyl Cellulose HPMC, Re tla leka ka matla ho boloka rekoto ea rona e ntle haholo re le mofani oa lihlahisoa tse ntlehali lefatšeng. Ha u na le lipotso kapa maikutlo, u lokela ho ikopanya le rona ka bolokolohi.
Boleng bo phahamengChina HPMC le Hydroxypropyl Methyl Cellulose, Re na le makala a 48 a liprofinse ka har'a naha. Re boetse re na le tšebelisano-'moho e tsitsitseng le lik'hamphani tse 'maloa tsa machaba tsa khoebo. Ba re fa odara le ho romela litharollo linaheng tse ling. Re lebeletse ho sebelisana le uena ho hlahisa 'maraka o moholoanyane.